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MORE
ON DR. POLASCIK
Memberships
- Fellow, American College of Surgeons
- American Urological Association
- American Medical Association
- Society of Urologic Oncology
- Southeastern section AUA
- North Carolina Urological Association
- North Carolina Chapter, American College of Surgeons
- North Carolina Medical Society
- Society for Cryobiology
- American College of Surgeons Professional Association
- Society of Laparoendoscopic Surgeons
- The Johns Hopkins Medical and Surgical Association
- Phi Beta Kappa, 1986
- Alpha Sigma Nu National Jesuit Honor Society, 1986
Research
- "Ablation of small renal tumors using radiofrequency energy in a rabbit model" Johns Hopkins University, 1997-98
- “Molecular genetics of small (<0.5cm) renal lesions” Johns Hopkins and Duke University, 1998-99
- "Hypertonic saline-enhanced radiofrequency ablation of renal tumors in a rabbit model: A survival study." Duke University Medical Center, 1998-99
- "Laparoscopic renal tissue ablation in a swine model using hypertonic saline-enhanced radiofrequency energy." Duke University Medical Center, 1998-present
- "Detection of circulating kidney cells in patients with renal malignancy" Duke University Medical Center, 1998-present
- Urologix “Proximal Ablation Trial #280011” for treatment of benign prostatic hyperplasia Duke University Medical Center, 1999 (co-investigator)
- Prospective evaluation of a trestle stenting device on patients experiencing urinary retention. Duke University Medical Center, 1999 (co-investigator)
- "A feasibility study of performing interposition nerve grafts in patients undergoing radical perineal prostatectomy with sacrifice of neurovascular bundles" Duke University Medical Center, 2000 (co-investigator)
- "Detection of circulating prostate cancer cells in patients with advanced prostate cancer." Duke University Medical Center, 2000.
- "Molecular characterization of low-grade collecting duct carcinomas of the kidney." Duke University Medical Center, 2000.
- "Molecular characterization of renal medullary carcinoma." Duke University Medical Center, 2000.
- "Renal cryotherapy: dosimetry studies using single and double probe techniques in the swine model." Duke University Medical Center, 2000.
- "Use of the laparoscopic bipolar coagulating forceps to secure the renal vasculature in the swine model." Principal Investigator Duke University Medical Center, 2000.
- "PET imaging of prostate cancer." (Co-investigator) Duke University Medical Center, 2000.
- "Noninvasive diagnosis of prostate cancer using PET imaging with 18F fluorocholine" (Co-investigator). Duke University Medical Center, 2001
- "Radiofrequency ablation of renal medulla and cortex with contrast-enhanced ultrasound: acute and chronic findings" (PI). Duke University Medical Center, 2002-03.
- "Understanding the potential risks of renal radiofrequency ablation: worst case scenarios (PI)." Duke University Medical Center, 2002-03.
- "Understanding potential risks of renal cryotherapy: worst case scenarios" (PI). Duke University Medical Center, 2002-03.
- “An open label trial evaluating the safety and efficacy of zoledronic acid in preventing bone loss in hormone-sensitive prostate cancer patients with bone metastases” Novartis Clinical Trial, Principal Investigator 2003-04.
- "Efficacy of ProstaScint scan to image lymphatic metastases in advanced prostate cancer." Principal Investigator 2002-2005.
- "Can local uptake only on ProstaScint scan predict response to salvage external beam radiotherapy after failed radical prostatectomy?" Principal Investigator 2002-2005.
- "Psychobiology of male sexual dysfunction following treatment of prostate cancer." Principal Investigator, Duke University Medical Center, 2002.
- “A randomized double-blind placebo-controlled study to evaluate AMG 162 in the treatment of bone loss in subjects undergoing androgen-deprivation therapy for non-metastatic prostate cancer” Principal Investigator 2004-2006.
- “EPIC study for prostate cancer” Co-investigator, 2004+
- “The effect of lowering central venous pressure on blood loss in patients undergoing radical retropubic prostatectomy under general anesthesia” Principal Investigator 2005
- “Lidocaine patch (Lidoderm) for analgesia following radical retropubic prostatectomy” Principal Investigator 2005
- “A phase I dose-escalation study of radiation therapy followed by cryotherapy in patients with intermediate risk clinically localized carcinoma of the prostate” Principal Investigator 2005
- “Innovations in cancer cell and tissue preservation.” Application for NIH NCI SBIR grant 2005
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Presentations
- "The complications associated with partial nephrectomy
for tumor." Podium session. Mid-Atlantic section
52nd annual meeting, October 1994, Philadelphia.
- "Partial nephrectomy: technique, complications
and pathological findings." Podium session. Annual
Maryland Urological Association, December 1994,
Baltimore.
- "Frequent loss of heterozygosity on chromosome
arms 8p and 13q in collecting duct carcinoma of
the kidney." Poster session: kidney neoplasms-basic
III. AUA 90th annual meeting, April 1995, Las Vegas.
Best poster award.
- "Intraoperative sonography for the evaluation
and management of renal tumors: experience with
100 patients." Podium session: kidney neoplasms-clinical
II. AUA 90th annual meeting, April 1995, Las Vegas.
- "Partial nephrectomy: technique, complications
and pathological findings." Podium session: kidney
neoplasms-clinical II. AUA 90th annual meeting,
April 1995, Las Vegas.
- "Microsatellite allelotype of chromosome 4 in
human invasive bladder carcinoma." Podium session:
bladder cancer-molecular markers and prognosis.
AUA 90th annual meeting, April 1995, Las Vegas.
- "Reappraisal of the role of human chorionic gonadotropin
for the diagnosis and treatment of the nonpalpable
testis: a 10-year experience." Podium session.
Am Acad Pediatrics, Section of Urology, October
1995, San Francisco.
Annual Maryland Urological Association, December
1995, Baltimore.
- "Distal nephron renal tumors: microsatellite allelotype."
Poster session. AUA 91th annual meeting, May 1996,
Orlando, FL.
- "Intraoperative ultrasound for renal tumors: its
importance in partial nephrectomy." Podium session.
Mid-Atlantic section 54th annual meeting, October
1996, Washington DC.
- "Long-term survival after radical nephrectomy
with intrahepatic or supra-diaphragmatic intracaval
thrombectomy for renal cell carcinoma." Podium session:
kidney neoplasms - clinical. AUA 92nd annual meeting,
April 1997, New Orleans.
- "Intraoperative color Doppler and power Doppler
sonography: improved technical advantages with partial
nephrectomy for renal tumors." Podium session: kidney
neoplasms - clinical. AUA 92nd annual meeting, April
1997, New Orleans.
- "Long-term survival after radical nephrectomy
with intrahepatic or supradiaphragmatic intracaval
thrombectomy for renal cell carcinoma." Oral session:
kidney cancer. SIU 24th Congress, September 1997,
Montreal, Canada.
- "The use of percent free prostate-specific antigen
for staging of men with clinically localized prostate
cancer." Oral session: prostate cancer. Mid Atlantic
section 55th annual meeting, September 1997, Hot
Springs, Virginia.
- "Comparison of staging algorithms and a monoclonal
antibody scan (ProstaScint) to predict lymph node
involvement in high-risk prostate cancer." Poster
session: staging and prognosis. AUA 93rd annual
meeting, June 1998, San Diego.
- "Harvest of intact prostate cancer cells from
blood: Further characterization of a new assay."
Poster session: prostate cancer, basic research.
AUA 93rd annual meeting, June 1998, San Diego.
- "Lack of cadherin-6 expression is correlated with
disease progression in clear cell renal cell carcinoma."
Poster session: kidney cancer, research. AUA 93rd
annual meeting, June 1998, San Diego.
- "Ablation of renal tumors in a rabbit model with
interstitial saline augmented radiofrequency energy:
Preliminary report of a new technology." Poster
session, 16th World Congress on Endourology and
SWL, Sept 3, 1998, New York.
- “Laparoscopic repair of retrocaval ureter.” Video
session, Southeastern AUA, March 1999, Charleston.
- “Ablation of renal tumors in a rabbit model with
interstitial saline augmented radiofrequency energy:
Preliminary report of a new technology.” Poster
session, AUA 94th annual meeting, May 1999, Dallas.
- "Survey of neuromuscular injuries to the patient
and surgeon during urologic laparoscopic surgery."
Poster session, 17th World Congress on Endourology,
September 1999, Rhodes, Greece.
- “p27 staining of circulating prostate cancer cells
does not correlate with pathologic stage.” Poster
session, 6th annual CaPCure meeting, October 1999,
Lake Tahoe, NV.
- "Interstitial saline augmented radiofrequency
ablation of renal tumors: further evaluation of
a new technology." Poster session, AUA 95th annual
meeting, May 2000, Atlanta, GA.
- Demark-Wahnefried W, Price DT, Polascik TJ, Anderson
EE, Robertson CN, Walther P, Paulson DF, Gannon
M and Vollmer R: Effect of short-term flaxseed supplementation
and fat modification in men with prostatic carcinoma.
Cancer Epidemiol Biomarkers Prev 9:235, 2000.
- Demark-Wahnefried W, Price DT, Polascik TJ, Anderson
EE, Robertson CN, Walther P, Paulson DF, Gannon
M and Vollmer R: Short-term flaxseed supplementation
and fat restriction in men with prostate cancer:
Effects on Prostate-specific antigen (PSA), hormonal
factors and proliferation rates. Abstract #3029.
Proceedings of the American Association for Cancer
Research, 41: 475, 2000.
- Demark-Wahnefried W, Price DT, Polascik TJ, Anderson
EE, Robertson CN, Walther P, Paulson DF, Gannon
M and Vollmer R: Presurgical fat restriction and
flaxseed supplementation among men with prostate
cancer: Effects on PSA, hormonal factors and proliferation
rates. Abstract #1301, J Urol 163: 293, 2000.
- Demark-Wahnefried W, Price DT, Polascik TJ, Anderson
EE, Robertson CN, Walther P, Paulson DF, Gannon
M and Vollmer R: Fat restriction and flaxseed supplementation
in men with prostate cancer: Effects on Prostate-specific
antigen (PSA), hormonal and histopathological markers.
J Amer Diet Assn 100:A-21, 2000.
- Demark-Wahnefried W, Price DT, Polascik TJ, Anderson
EE, Walther P, Paulson DF, Gannon M and Vollmer
R: Presurgical fat restriction and flaxseed supplementation
among men with prostate cancer: Effects on PSA,
hormonal factors and proliferation rates. J Nutrition
(in press).
- "Hypertonic interstitial saline-augmented radiofrequency
ablation of renal tumors: assessment of a new technology
for laparoscopic or percutaneous application." 9th
International Meeting of Laparoendoscopic Surgeons,
SLS Annual meeting, ENDO EXPO 2000, Orlando, FL,
Dec 2000.
- "Hand-assisted laparoscopic nephrectomy: Preliminary
experience." 9th International Meeting of Laparoendoscopic
Surgeons, SLS Annual meeting, ENDO EXPO 2000, Orlando,
FL, Dec 2000.
- "Factors influencing return to employment following
laparoscopic renal surgery." Southeastern AUA, New
Orleans, May 2001.
- "Hand-assisted laparoscopic nephrectomy for the
scarred kidney." Southeastern AUA, New Orleans,
May 2001.
- "Utility of capromab pendetide imaging to detect
recurrent disease after radical prostatectomy."
Southeastern AUA, New Orleans, May 2001.
- Raj GV, Partin AW and Polascik TJ: "Utility of
capromab pendetide to image early recurrent disease
after radical prostatectomy." American Urological
Association annual meeting, Anaheim CA June 2-7,
2001
- DeGrado TR, Wang S, Baldwin SW, Orr MD, Robertson
CN, Polascik TJ, Kelley MJ, Liao R, Coleman RE and
Price DT: "F-18 labeled choline analogs as PET imaging
probes of prostate cancer." American Urological
Association annual meeting, Anaheim CA June 2-7,
2001
- "Comparison of F-18 fluorocholine and FDG in PET
imaging of androgen-dependent and androgen-independent
prostate cancer." Academy of Molecular Imaging,
Orlando FL October 24-28, 2001.
- "Use of bipolar laparoscopic forceps to occlude
and transect the retroperitoneal vasculature: a
porcine model." World Congress of Endourology, Bangkok,
Thailand, November 2001.
- "Cryoablation parameters using swine renal tissue."
World Congress of Endourology, Bangkok, Thailand,
November 2001.
- "Effects of a low fat, flaxseed-supplemented diet
on men with prostatic intraepithelial neoplasia
(PIN) or atypia." AACR Frontiers in Cancer Prevention
Research Conference, Boston, MA, October 14-18,
2002.
- "Does a prior negative prostate biopsy predict
outcome for patients treated with radical perineal
prostatectomy?" Society of Urologic Oncology, NIH,
Bethesda MD December 13-14, 2002.
- "Renal cryosurgery: Worst case scenarios in a
porcine model." Dept of Anesthesiology Eleventh
Annual Academic Evening, Duke University, Durham
Hilton, Durham, NC, May 6, 2003.
- "Renal radiofrequency ablation: Worst case scenarios
in a porcine model." Dept of Anesthesiology Eleventh
Annual Academic Evening, Duke University, Durham
Hilton, Durham, NC, May 6, 2003.
- “Radiofrequency ablation: worst case scenarios
in a porcine model” North Carolina Urologic Resident
Seminar, Greensboro NC, November 8, 2003.
- Renal radiofrequency ablation: worst case scenarios
in a porcine model. AARS 2004.
- “Renal radiofrequency ablation versus cryosurgery:
Understanding short-term complications in a porcine
model” Society of Urologic Oncology, NIH, Bethesda
MD Dec 5, 2003.
- Renal cryosurgery: worst case scenarios in a porcine
model. XIXth EUA Congress, Vienna Austria March
24-27, 2004.
- Renal radiofrequency ablation: worst case scenarios
in a porcine model. XIXth EUA Congress, Vienna Austria
March 24-27, 2004.
- Characteristics of patients with complications
following percutaneous radiofrequency ablation of
renal tumors. SEAUA 68th annual meeting March 24-27,
2004, Aruba.
- Renal radiofrequency ablation: worst case scenarios
in a porcine model. SEAUA 68th annual meeting March
24-27, 2004, Aruba.
- Renal radiofrequency ablation: worst case scenarios
in a porcine model. American Roentgen Ray Society,
104th annual meeting, May 2-7 2004 Miami Beach.
- Renal cryoablation and radiofrequency ablation:
an evaluation of worst case scenarios in a porcine
model. Presented at the Urology Residents and Fellows
Forum of Excellence, AUA meeting May 13, 2004 San
Francisco, CA.
- An open label trial of the effect of zoledronic
acid on bone mineral density in hormone sensitive
prostate cancer patients with bone metastases. AUA
Western sectional meeting, August 2004.
- Characteristics of patients with complications
following percutaneous radiofrequency ablation of
renal tumors. Society of Urologic Oncology, NCI/NIH,
December 3, 2004.
- Does a prior benign prostate biopsy predict outcome
for patients undergoing a radical perineal prostatectomy?
2005 Multidisciplinary Prostate Cancer Symposium,
ASCO, Orlando, FL, February 17-19, 2005.
- An open-label trial of the effect of zoledronic
acid on bone mineral density in hormone-sensitive
prostate cancer patients with bone metastasis. Podium
session, Southeastern American Urological Assn annual
sectional meeting, Charleston SC, March 6, 2005.
- Intentional cryosurgical injury of vital renal
structures in a porcine model. Podium session, Southeastern
American Urological Assn Annual Meeting, Charleston
SC, March 5, 2005.
- Renal cryoablation and radiofrequency ablation:
an evaluation of worst case scenarios in a porcine
model. Podium session, American Urological Assn
Annual Meeting, San Antonio TX, May 21-26, 2005.
- Characteristics of patients with complications
following percutaneous radiofrequency ablation of
renal tumors. Poster session, American Urological
Assn Annual Meeting, San Antonio TX, May 21-26,
2005.
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