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Research and News  About Prostate Cancer

PROSTATE CANCER RESEARCH & NEWS

Treatment of Organ Confined Prostate Cancer with Third Generation Cryosurgery:
Preliminary Multicenter Experience

Ken-Ryu Han, Jeff K. Cohen, Ralph J. Miller, Allan J. Pantuck, Danielo G. Freitas, Carlos A. Cuevas, Hyung L. Kim, James Lugg, Stacy J. Childs, Barry Shuman, Maury A. Jayson, Neal D. Shore, Yan Moore, Amnon Zisman, Joe Y. Lee, Roland Ugarte, Lance A. Mynderse, Torrence M. Wilson, Susan D. Sweat, Horst Zincke and Arie Belldegrun
The Journal of Urology Vol. 170, pp. 1126-1130, October 2003
©2003 American Urological Association

Multicenter Initial U.S. Experience with Coretherm Monitored Feedback Transurethral Microwave Thermotherapy for Individualized Treatment of Patients with Symptomatic Benign Prostatic Hyperplasia
R. David, MD, N. Shore, MD, et al Journal of Endourology, Vol. 18, No. 7, September 2004.

Thermal Therapy Adjuvant To Temperature Sensitive Liposomal Encapsulated Doxorubicin (Thermadox™) For The Treatment Of Prostate Cancer.
Prostate Cancer Foundation, NY, NY, November 2003; Poster Presentation

Detection of Circulating tumor Cells in the Peripheral Blood of Urogenital Tract Cancer Patient (PTS) By the Enriched Immunocytochemical (EICC) Assay
Lyass, O., Moss, T., Umiel, T. Prilutskaya, Freedman, S., Shore, N.D.; AUA 2002. (Submitted)

Perianal Lipoma Versus Renal Cell Carcinoma.
Mydello, J., Shore, N.D., Rueter, V. and Herr, H.W.; Urology. (Submitted)

Renal Cell Metastases Versus Liver Meningioma.
Mydello, J., Shore, N.D., Herr, H.W.; Urology. (Submitted)

Evaluation of pre-ESWL Stenting and Local Anesthesia for Shock Wave Lithotripsy at a Single University Center.
Shore, N.D., Sommers, W., Riehle, R.A., Jr.; Journal of Urology. (Accepted)

Evaluation and Treatment of Pyelocaliectasis in Infancy.
Mininberg, D.T. and Shore, N.D.; Problems in Urology. Eds. Paulson and King, Volume 2, Number 1, Chapter 4, J.B. Lippincott Company, Philadelphia, PA, 1988.

Indwelling Ureteral Stents.
Shore, N.D. Bregg, K.J., Sosa, R.E.; Seminar in Urology, 5: 200-207, August 1987.

The Best Suture for Hypospadias?
Bartone, F., Shore, N.D., Newland, J., King, L.R. and DuPlesis, D.; Urology, 29: 517-522, May, 1987.

Balloon Dilatation of Upper Ureteral Structures in Primates.
Shore, N.D., Bartone, F., Miller, A., King, L.R. and DuPlesis, D.; Journal of Urology, 136; 342-343, July 1986.

Free Autogenous Muscle Transplantation in Rabbits: A Technique for Correction of Urinary Incontinence.
Shore, N.D., Schachat, F., and King, L.R.: Journal of Urology, 134; 1047-1049, November 1985.

Balloon Dilatation of Ureteral Strictures in Dogs.
El-Mahrouky, A., Ford, K., Shore, N.D., and King, L.R.; Journal of Urology, 131: 582-586, March 1984.

Urolithiasis: Evaluation and Management
Krzyzaniak, K.E., Jour. of S. C. Med. Assoc. 78:12, p. 678, 12/19/82.

Inhibition of Renin Secretion by HC1 is Related to Chloride in Both Dogs and Rats
Kotchen, Krzyzaniak, et al., Amer. Jour. of Physiology. Vol. 239, #1, F44, July, 1980.

Primary Carcinoid Tumor of Urinary Bladder
Yang, Krzyzaniak, et al., Urology, Vol. 27, No. 6, pgs. 594-597, December, 1985.

Diseases of the Prostate, Family Medicine: Principles and Practice, 4th Edition
Epperson, William J. and Krzyzaniak, K.E. Co-Author Chapter 100. Springer Verlag, N.Y.

Ureteroduodenal Fistula
Roberts B., et al: Urology, August, 1996

Urinary Tract Infections in Children
Roberts, B., Gibbons M.: Advances, May, 1997

Delayed Management of Neonatal Hydronephrosis: Results of Ten Year Follow-Up
Roberts, B., Mordkin, R.: Pending Publication.

The Use of Artificial Neural Networks to Predict Treatment Outcome after Transurethral Thermotherapy
Roberts B., Lynch, J., Regan J., et al: Pending publication.

Pelvic Lipomatosis
Mordkin, M., Roberts, B.: Contemporary Surgery. Pending publication.

Surgical Rounds; Surgical Study Guide for Students
Contributing Author.

Calcium Channel Antagonists Prevent Urinary Bladder Growth and Neuroplasticity Following Mechanical Stress
Steers, W., Albo, M., et al: Am. J. Physiol., Jan., 1994

Neomycin cannot be used as a selective inhibitor of inositol phospholipid hydrolysis in intact or semi-permeabilized human platelets.
Polascik T, Godfrey PP and Watson SP: Biochem J 243(3) 815, 1987.

Synergistic effects of calcium channel blockers vs. ACE-inhibitors with diuretics in lowering blood pressure.
Elliott WJ, Polascik TJ and Murphy MB: Am J Hypertension 2: 42A, 1989.

Verapamil and diuretic lowers blood pressure as effectively as enalapril and diuretic.
Elliott WJ, Polascik T and Murphy MB: Clin Res 37: 903A, 1989.

Enalapril, but not verapamil, blunts changes in serum chemistries when used with diuretics.
Elliott WJ, Polascik T and Murphy MB: Am J Hypertension 3: 105A, 1990.

Equivalent antihypertensive effects of combination therapy using diuretic + calcium antagonist compared with diuretic + ACE-inhibitor.
Elliott WJ, Polascik TJ and Murphy MB: J Human Hypertension 4(6) 717, 1990.

Comparison of laparoscopic and open retropubic urethropexy for treatment of stress urinary incontinence.
Polascik TJ, Moore RG, Rosenberg MT and Kavoussi LR: Urology 45: 647, 1995.

Radical retropubic prostatectomy the influence of accessory pudendal arteries on the recovery of sexual function.
Polascik TJ and Walsh PC: J Urol 153: 150, 1995.

Radical prostatectomy in men less than 50 years old.
Riopel MA, Polascik TJ, Partin AW, Sauvageot J, Walsh PC, and Epstein JI: Urol Oncol 1 80, 1995.

Novel suppressor loci on chromosome 14q in primary bladder cancer.
Chang WYH, Cairns P, Schoenberg MP, Polascik TJ and Sidransky D: Cancer Research 55: 3246, 1995.

Distinct regions of allelic loss on chromosome 4 in human primary bladder carcinoma.
Polascik TJ, Cairns P, Chang WYK, Schoenberg MP and Sidransky D: Cancer Research 55: 5396, 1995.

High frequency of homozygous deletion at p16/CDKN2 in primary human tumors.
Cairns P, Polascik TJ, Eby Y, Tokino K, Califano J, Merlo A, Mao L, Herath J, Jenkins R, Westra W, Rutter JL, Buckler A, Gabrielson E, Tockman M, Cho K, Hedrick L, Bova GS, Isaacs W, Koch W, Schwab D and Sidransky D: Nature Genetics 11: 210, 1995.

Partial nephrectomy technique, complications and pathological findings.
Polascik TJ, Pound CR, Meng MV, Partin AW and Marshall FF: J Urol 154: 1312, 1995.

Intraoperative sonography for the evaluation and management of renal tumors experience with 100 patients.
Polascik TJ, Meng MV, Epstein JI and Marshall FF: J Urol 154: 1676, 1995.

Reappraisal of the role of human chorionic gonadotropin in the diagnosis and treatment of the nonpalpable testis: A 10-year experience.
Polascik TJ, Chan-Tack KM, Jeffs RD and Gearhart JP: J Urol 156: 804, 1996.

Distal nephron renal tumors: microsatellite allelotype.
Polascik TJ, Cairns P, Epstein JI, Fuzesi L, Ro JY, Marshall FF, Sidransky D and Schoenberg MP: Cancer Research 56: 1892, 1996.

High-density mapping of chromosomal arm 1q in renal collecting duct carcinoma region of minimal deletion at 1q32.1-32.2.
Steiner G, Cairns P, Polascik TJ, Marshall FF, Epstein JI, Sidransky D and Schoenberg M: Cancer Research 56: 5044, 1996.

Intraoperative sonographic evaluation of the kidney.
Polascik TJ and Marshall FF: AUA Update Series, Vol. XVI, No. 18, 1997.

Multivariate models as predictors of pathological stage using Gleason score, clinical stage and serum prostate-specific antigen.
Polascik TJ, Pearson JD and Partin AW: Seminars in Urologic Oncology 16 :160-171, 1998.

Laparoscopic ureteroureterostomy for retrocaval ureter.
Polascik TJ and Chen R: J Urol 160 :121, 1998.

Frequent occurrence of metastatic disease in patients with renal cell carcinoma and intrahepatic or supradiaphragmatic intracaval extension treated with surgery: an outcome analysis.
Polascik TJ, Partin AW, Pound CR and Marshall FF: Urology 52 :995-999, 1998.

Prostate-specific antigen 1998: What we have learned and where we are going. Part I Clinical utility of PSA for the detection of prostate cancer.
Polascik TJ, Oesterling, JE and Partin AW: AUA Update Series, Vol. 17, No. 27, 1998.

Prostate-specific antigen 1998: What we have learned and where we are going. Part II Detection, staging and monitoring of prostate cancer.
Polascik TJ, Oesterling, JE and Partin AW: AUA Update Series, Vol. 17, No. 28, 1998.

Multivariate analysis: Predicting pathologic stage of prostate cancer with PSA.
Polascik TJ and Partin AW: Contemporary Urology 10:76-79,1998.

Comparison of radical prostatectomy and 125I interstitial radiotherapy for the treatment of clinically localized prostate cancer: A 7-year biochemical (PSA) progression analysis.
Polascik TJ, Pound CR, DeWeese TL and Walsh PC: Urology 51: 884, 1998.

Use of multivariate models to improve prediction of pathologic stage for men with clinically localized prostate cancer.
Polascik TJ, Pearson JD and Partin AW: Prostate Cancer and Prostatic Diseases 5:1-6, 1998.

Prostate-specific antigen: A decade of discovery - What we have learned and where we are going.
Polascik TJ, Oesterling JE and Partin AW: J Urol 162:293-306, 1999.

Comparison of clinical staging algorithms and 111Indium-capromab pendetide immunoscintigraphy in the prediction of lymph node involvement in high-risk prostate carcinoma patients.
Polascik TJ, Manyak MJ, Haseman M, Gurganus RT, Rogers B, Maguire RT and Partin AW: Cancer 85: 1586-1592, 1999.

Ablation of renal tumors in a rabbit model with interstitial saline augmented radiofrequency energy: Preliminary report of a new technology.
Polascik TJ, Hamper U, Lee BR, Dai Y, Hilton J, Magee CA, Crone JK, Shue MJ, Ferrell M, Adiletta M and Partin AW: Urology 53: 465-472, 1999.

Influence of sextant prostate needle biopsy or surgery on the detection and harvest of intact circulating prostate cancer cells.
Polascik TJ, Wang ZP, Shue M, Di S, Gurganus R, Hortopan S, Ts'O POP and Partin AW: J Urol 162: 749-52, 1999.

Capromab pendetide imaging of prostate cancer.
Haseman MK, Rosenthal SA and Polascik TJ: Cancer Biotherapy and Radiopharmaceuticals, 15: 131-140, 2000.

Survey of neuromuscular injuries to the patient and surgeon during urologic laparoscopic surgery.
Wolf JS, Marcovich R, Gill IS, Sung GT, Kavoussi LR, Clayman RV, McDougall EM, Shalhav A, Dunn MD, Afane JS, Moore RG, Parra RO, Winfield HN, Sosa RE, Chen RN, Moran ME, Nakada SY, Hamilton BD, Albala DM, Koleski F, Das S, Adams JB and Polascik TJ: Urology 55: 831-6, 2000.

Advances in DVT prophylaxis in Urology.
Raj G, Subramanian SV and Polascik TJ: Contemporary Urology 12 (9): 56, 2000.

HIV infection presenting as an unusually large pure yolk sac tumor of the testis.
Munver R, Donehower RC, Kronz JD and Polascik TJ: J Urol 164: 1653-54, 2000.

Synthesis and evaluation of 18F-labeled choline as an oncologic tracer for positron emission tomography
initial findings in prostate cancer.

DeGrado TR, Coleman RE, Wang S, Baldwin SW, Orr MD, Robertson CN, Polascik TJ and Price DT: Cancer Research 61:110-117, 2001.

Management of small renal tumors: an overview.
Reddan DN, Raj GV and Polascik TJ: Am J Med 110:558-562, 2001.

Utility of capromab pendetide (ProstaScint) imaging in the management of prostate cancer.
Rosenthal SA, Haseman MK and Polascik TJ: Techniques in Urology 7:27-37, 2001.

Partial nephrectomy for renal tumors.
Polascik TJ and Marshall FF: AUA Update Series, Vol. 20, No. 21, 2001.

Pilot study of dietary fat restriction and flaxseed supplementation in men with prostate cancer before surgery: Exploring the effects on hormonal levels, prostate-specific antigen, and histopathologic features.
Demark-Wahnefried W, Price DT, Polascik TJ, Robertson CN, Anderson EE, Paulson DF, Walther PJ, Gannon M and Vollmer RT: Urology 58: 47-52, 2001.

Clinical utility of 111In-Capromab pendetide immunoscintigraphy in the detection of early recurrent prostate cancer after radical prostatectomy.
Raj GV, Partin AW and Polascik TJ: Cancer 94: 987-996, 2002.

Comparison of [18F] Fluorocholine and [18F] Fluorodeoxyglucose for positron emission tomography of androgen dependent and androgen independent prostate cancer.
Price DT, Coleman RE, Liao RP, Robertson CN, Polascik TJ and DeGrado TR: J Urology 168: 273-280, 2002.

Hypertonic saline-augmented radiofrequency ablation of the VX-2 tumor implanted in the rabbit kidney: A short-term survival pilot study.
Munver R, Threatt CB, Delvecchio FC, Preminger GM and Polascik TJ: Urology 60: 170-175, 2002.

Molecular genetics and histopathologic features of adult distal nephron tumors.
Polascik TJ, Bostwick DG and Cairns P: Urology 60: 941-946, 2002.

Management of the small renal tumor with radiofrequency ablation.
Raj GV, Reddan DJ, Hoey MB, and Polascik TJ: Urology 61:23-29, 2003.

Autoimmune testicular vasculitis.
Raj GV, Ellington KS, and Polascik TJ: Urology 61: 1035, 2003.

Use of bipolar laparoscopic forceps to occlude and transect the retroperitoneal vasculature: A porcine model.
Santa-Cruz RW, Auge BK, Lallas CD, Preminger GM and Polascik TJ: J Endourology 17 (3): 181-5, 2003.

An exploratory study of the effects of a low-fat, flaxseed -supplemented diet on proliferation of benign prostatic epithelium and prostate-specific antigen.
Demark-Wahnefried W, Robertson CN, Walther PJ, Polascik TJ, Paulson DF, and Vollmer RT: Urology 63: 900-904, 2004.

Promoter hypermethylation profile of kidney cancer.
Dulaimi E, Ibanez de Caceres I, Uzzo RG, Al-Saleem T, Greenberg RE, Polascik TJ, Babb JS, Grizzle WE and Cairns P: Clin Can Res 10: 3972-79, 2004.

Does prior benign prostate biopsy predict outcome for patients treated with radical perineal prostatectomy?
Raj GV, Brashears JH, Anand A, Paulson DF and Polascik TJ: (in press, Urology June 2005).

Renal cryoablation and radiofrequency ablation: an evaluation of worst case scenarios in a porcine model.
Brashears JH, Raj GV, Crissi A, Young MD, Dylewski D, Nelson R, Madden JF and Polascik TJ: Journal of Urology 173: 2160-65, 2005.

ProstaScintTM (Capromab Pendetide) Imaging Technique Using a Hybrid Gamma-CT Camera.
Wong TZ, Turkington TG, Polascik TJ, and Coleman RE: In press, AJR 2005

Ovarian hyperstimulation causing ureteral obstruction in the gravid female.
Wiygul JB, Lallas C, Silverstein A, and Polascik TJ: (in press Urology 2005).

Supplement use among men with prostate cancer.
Wiygul JB, Evans BR, Peterson BL, Polascik TJ, Walther PJ, Robertson CN, Albala DM, and Demark-Wahnefried W: Urology 66:161-66, 2005.

An open-label trial evaluating the safety and efficacy of zoledronic acid in preventing bone loss in hormone-sensitive prostate cancer patients with bone metastases.
Polascik TJ, Given RW, Metzger C, Julian SR, Vestal JC, Karlin GS, Barkley CS, Bilhartz DL, Lacerna LV, Petrone SE and McWhorter LT: (in press, Urology November 2005).

Complications following percutaneous radiofrequency ablation of renal tumors.
Weizer A, Raj GV, Nelson R, Robertson C and Polascik TJ: (in press Urology December 2005).

Salvage Prostate Cryoablation after primary Interstitial Brachytherapy Failure: a feasible approach.
Mouraviev V, Evans B , and Polascik TJ: In Prostate Cancer and Prostatic Diseases (in press 2005).

The effect of freeze time during renal cryoablation: a swine model.
Auge BK, Santa-Cruz RW, Polascik TJ: (submitted, J Endourology 2005).

Malignant cystic nephroma in an adult
Raj GV, Yowell C, Madden J, and Polascik TJ: (submitted Int J Urology, 2005)

Rectourethral fistula after combination radiotherapy for prostate cancer.
Marguet C, Raj GV, Brashears JH, Anscher MS, Ludwig K, Polascik TJ and Robertson CN: (submitted Urology 2005).

Age-adjusted PSAV improves prostate cancer detection.
Hotaling J, Sun L, Moul J, Scales C, Pappas P, Polascik T, Robertson C, George D, Donatucci C and Anscher M

Effect of positive surgical margins on PSA recurrence in men with diagnostic PSA 10-20, pT2b, and Gleason score 7 the intermediate risk challenge.
Fitzsimons N, Sun L, Robertson C, Polascik T, Donatucci C, and Moul J

Epidemiology of prostate cancer: Duke's experience in the past three decades.
Sun L, Moul J, Donatucci C, Dahm P, Anscher M, Robertson C, Polascik T, Albala D, Walther P and George D

Renal tumors less than 0.5 cm: incidence and biologic significance.
Cairns P, Raj G and Polascik TJ: (In preparation), 2005.

Xanthogranulomatous pyelonephritis radiographically simulating renal tuberculosis.
Henry G, Leder R and Polascik TJ: (In preparation), 2005.

Minimally invasive therapies for small < 3 cm renal tumors: cryotherapy vs radiofrequency ablation.
Raj G and Polascik TJ: (In preparation, 2005)

Utility of a novel ultrasound contrast agent in real-time imaging of renal ablative lesions in a porcine model.
Brashears JH, Raj GV, Nelson RA and Polascik TJ

Treatment of bilateral interpolar renal cell carcinoma with minimally invasive ablative approaches.
Marguet CG, Brashears JH, Raj GV, Nelson R, and Polascik TJ: (submitted Urology 2005).

“The effect of lowering central venous pressure on blood loss in patients undergoing radical retropubic prostatectomy under general anesthesia”
Principal Investigator 2005

“Lidocaine patch (Lidoderm) for analgesia following radical retropubic prostatectomy”
Principal Investigator 2005

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Dr. Neal Shore
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Dr. Thomas Polascik
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Duke Univ Medical Center
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(919) 684-4946

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